Extented measures for controlling an outbreak of VIM-1 producing imipenem-resistant Klebsiella pneumoniae in a liver transplant
نویسندگان
چکیده
N Kassis-Chikhani ([email protected])1,2, F Saliba3, A Carbonne4, S Neuville5, D Decre6,7,8, C Sengelin1,2, C Guerin1, N Gastiaburu3, A Lavigne-Kriaa3, C Boutelier1, G Arlet7,8,9, D Samuel3,10, D Castaing3,10, E Dussaix2,10, V Jarlier5,7,11 1. Assistance Publique–Hôpitaux de Paris, hospital Paul Brousse, Infection Control Unit, Villejuif, France 2. Assistance Publique–Hôpitaux de Paris, hospital Paul Brousse, Microbiology Laboratory, Villejuif, France 3. Assistance Publique–Hôpitaux de Paris, hospital Paul Brousse, Centre Hépato-Biliaire, Villejuif, France 4. Centre de Coordination de la Lutte contre les Infections Nosocomiales (CCLIN, Coordinating centre in the fight against nosocomial infections) Paris-Nord, France 5. Assistance Publique–Hôpitaux de Paris, Central Infection Control Team, Paris, France 6. Assistance Publique–Hôpitaux de Paris, hospital Saint-Antoine, Bacteriology, Paris, France 7. Université Pierre et Marie Curie, Paris 6, France 8. ER8 Antibiotiques et Flore digestive, Université Paris 6, Paris, France 9. Assistance Publique–Hôpitaux de Paris, hospital Tenon, Bacteriology, Paris, France 10. Université Paris-Sud, UMR 785, Villejuif, France 11. Assistance Publique–Hôpitaux de Paris, hospital Pitié-Salpétrière, Paris, France
منابع مشابه
Outbreak caused by a multidrug-resistant Klebsiella pneumoniae clone carrying blaVIM-12 in a university hospital.
From November 2006 to April 2007, nine nonrepetitive isolates of Klebsiella pneumoniae with reduced susceptibility or resistance to carbapenems were recovered from clinical specimens from separate patients hospitalized in a tertiary care hospital. The imipenem-EDTA synergy test was positive for all isolates. PCR, sequencing, and transferability experiments revealed the novel bla(VIM-12) metallo...
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BACKGROUND AND OBJECTIVES The rapid emergence and dissemination of carbapenemase-producing Klebsiella pneumoniae strains and other members of the Enterobacteriaceae poses a considerable threat to the care of hospitalized patients and to public health. The aim of this study was to determine the frequency of metallo-β-lactamases (MBL) and VIM-1 gene in multidrug-resistant strains of K. pneumoniae...
متن کاملFirst outbreak of multidrug-resistant Klebsiella pneumoniae carrying blaVIM-1 and blaSHV-5 in a French university hospital.
OBJECTIVES We studied eight imipenem-resistant isolates of Klebsiella pneumoniae involved in an outbreak in a French teaching hospital. METHODS The eight isolates were recovered from clinical specimens or rectal swabs. Antibiotic susceptibilities were determined using standard agar diffusion and dilution methods including synergy tests. PFGE was used to study the relatedness of isolates. Gene...
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Klebsiella pneumoniae strains with the transferable carbapenem-hydrolyzing metallo-beta-lactamases, which include IMP- and VIM-type enzymes, remain extremely rare. To investigate whether IMP- or VIM-producing K. pneumoniae isolates had spread at a university medical center in Taiwan, a total of 3,458 clinical isolates of K. pneumoniae consecutively collected in 1999 and 2000 were tested by the ...
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Background and Aims: Klebsiella pneumoniae is a gram negative opportunistic pathogen of nosocomial infections that causes pneumonia, urinary tract infection (UTI), meningitis, septicemia and diarrhea. The emergence and spread of carbapenemase producing Klebsiella pneumoniae often cause failure in the treatment of infections. The aim of this study was to evaluate the prevalence of carbapenemase ...
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